Key result
An implantable motor-driven LVAD tested in 10 sheep achieved a mean pump flow of 1.63 L/min, with 4 animals surviving 5-12 hours before termination due to various complications.
Why the study?
Does a console-based implantable motor-driven left ventricular assist device provide adequate hemodynamic support in a sheep model?
Does a console-based implantable motor-driven left ventricular assist device provide adequate hemodynamic support in a sheep model?
Initial testing of a console-based implantable motor-driven LVAD in a sheep model demonstrated basic hemodynamic feasibility but was limited by early fatal complications, prompting further development of an ultracompact device.
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Acute hemodynamic support shown in sheep; leaves open long-term durability and clinical translation.
Kikugawa et al. (1999) studied this question. Implantable motor-driven left ventricular assist device (LVAD) was evaluated on Survival and pump flow. An implantable motor-driven LVAD tested in 10 sheep achieved a mean pump flow of 1.63 L/min, with 4 animals surviving 5-12 hours before termination due to various complications.
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