Why the study?
Does intravenous labetalol improve blood pressure response in severely hypertensive patients already receiving other antihypertensive agents?
Does intravenous labetalol improve blood pressure response in severely hypertensive patients already receiving other antihypertensive agents?
Intravenous labetalol bolus was found to be ineffective for managing hypertensive emergencies in patients already receiving other antihypertensive medications.
May not control BP with labetalol in pretreated hypertensive emergencies; leaves open need for prospective trials.
Labetalol, a combined alpha-blocking and beta-blocking agents, was administered by intravenous bolus to six severely hypertensive patients. The blood pressure response was unsatisfactory in every case. It is concluded that intravenous administration of labetalol is not useful in hypertensive emergencies which occur in patients who are already receiving other antihypertensive agents.
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A 1978 study studied this question.
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