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March 1, 1990Pacing and Clinical Electrophysiology

The Defibrillation Success Rate Versus Energy Relationship: Part I‐Curve Fitting and the Most Efficient Defibrillation Energy

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Key result

The exponential curve best describes the defibrillation success rate versus energy relationship, with the most efficient energy of 4.34 J achieving a 70% success rate.

Population

10 dogs (mean weight 20.5 +/- 1.5 kg) undergoing ventricular fibrillation

Design

Preclinical, randomly attempted at energies

Authors

BGBradford E. GlinerAtrium Health Wake Forest BaptistYMYuji MurakawaJapanese Society of Medical OncologyNTNitish V. ThakorNorthern Illinois University

Discussion

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Implication

Hypothesis-generating for defibrillator energy optimization in animals; leaves open translation to human ICD programming.

Structured PICO

P
Population
10 dogs weighing approximately 20.5 kg undergoing randomly attempted defibrillation trials during ventricular fibrillation.
I
Intervention
Defibrillation energy pulses at various energy levels
O
Outcome
Defibrillation success rate versus energy relationshipsurrogate

The relationship between defibrillation success rate and energy is best described by an exponential curve, which can help optimize energy efficiency in implantable defibrillators.

Cite This Study

Gliner et al. (1990) studied Ventricular fibrillation (n=10). Defibrillation energy pulse was evaluated on Defibrillation success rate versus energy relationship. The exponential curve best describes the defibrillation success rate versus energy relationship, with the most efficient energy of 4.34 J achieving a 70% success rate.

synapsesocial.com/papers/6a9674dda43071aed1f6a255https://doi.org/10.1111/j.1540-8159.1990.tb02046.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The relationship between successful defibrillation and delivered energy in open-chest dogs: Reappraisal of the “defibrillation threshold” concept1987 · 217 citations
  2. 2Defibrillation Threshold: A Simple and Quantitative Estimate of the Ability to Defibrillate1987 · 101 citations
  3. 3A Model to Evaluate Alternative Methods of Defibrillation Threshold Determination1988 · 28 citations
  4. 4Temporal stability and precision of ventricular defibrillation threshold data1978 · 33 citations
  5. 5Electrical Dose for Ventricular Defibrillation of Large and Small Animals Using Precordial Electrodes1974 · 139 citations