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November 1, 1988Pacing and Clinical Electrophysiology

A Model to Evaluate Alternative Methods of Defibrillation Threshold Determination

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Key result

Averaging the results of stepping down to the first failure and stepping up to the first success yielded lower total error in estimating the defibrillation threshold than either method alone.

Why the study?

Does a combined step-down and step-up averaging method reduce total error in determining defibrillation threshold compared to single-direction stepping methods?

Population

Published animal data and human clinical data for defibrillation threshold determination

Comparison

Method 3: stepping down to the first voltage… vs Method 1 and Method 2

Design

Other

Authors

TCTimothy R. ChurchUniversity of MinnesotaMMMelissa MartinsonMinnesota Medical AssociationMKMichael J. KallokWestern University

Discussion

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Implication

May improve DFT estimation accuracy during implantation; leaves open prospective validation and outcome impact before practice change.

Structured PICO

Does a combined step-down and step-up averaging method reduce total error in determining defibrillation threshold compared to single-direction stepping methods?

P
Population
Published animal data and human clinical data for defibrillation threshold determination
I
Intervention
Method 3: stepping down to the first voltage that fails, stepping up to the first voltage that succeeds, and averaging
C
Comparator
Method 1 (stepping down to the first voltage that fails) and Method 2 (stepping up to the first voltage that succeeds)
O
Outcome
Total error in estimating the true defibrillation threshold

Averaging the results of step-down and step-up methods provides a more accurate estimation of the true defibrillation threshold than either method alone.

Cite This Study

Church et al. (1988) studied Fibrillation. Method 3 (averaging step-down and step-up methods) vs. Method 1 (step-down) and Method 2 (step-up) was evaluated on Total error in estimating the true defibrillation threshold. Averaging the results of stepping down to the first failure and stepping up to the first success yielded lower total error in estimating the defibrillation threshold than either method alone.

synapsesocial.com/papers/6a9674dda43071aed1f6a256https://doi.org/10.1111/j.1540-8159.1988.tb06341.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Temporal stability and precision of ventricular defibrillation threshold data1978 · 33 citations
  2. 2Measurement of cardioversion/defibrillation thresholds in man by a truncated exponential waveform and an apical patch-superior vena caval spring electrode configuration.1984 · 109 citations
  3. 3Defibrillation Threshold: A Simple and Quantitative Estimate of the Ability to Defibrillate1987 · 101 citations
  4. 4The relationship between successful defibrillation and delivered energy in open-chest dogs: Reappraisal of the “defibrillation threshold” concept1987 · 217 citations