Population
Normal and dystrophic muscle from the Bar Harbor 129 Re strain of mice
Design
Preclinical
Authors
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Fibre splitting may confound biopsy interpretation in dystrophy; hypothesis-generating for human disease and requires validation.
Longitudinal fibre splitting in dystrophic mouse muscle contributes significantly to variations in fibre diameter and atrophic fibre grouping.
Isaacs et al. (1973) studied this question.
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