Key result
Failing bipolar polyurethane insulated pacing leads produced artifacts in 84.6% of cases (vs 0% in controls) and a significant decrease in impedance.
Why the study?
Do failing bipolar polyurethane insulated permanent pacing leads produce specific artifacts and impedance changes compared to normally functioning leads?
Observational (n=37)
Do failing bipolar polyurethane insulated permanent pacing leads produce specific artifacts and impedance changes compared to normally functioning leads?
Absolute Event Rate: 84.6% vs 0%
Failing bipolar polyurethane pacing leads exhibit specific spike artifacts and significant impedance drops, likely due to inner insulation short circuits, which can aid in clinical follow-up.
May flag failing polyurethane leads during interrogation; hypothesis-generating and requires prospective validation before changing follow-up.
Pacing failure in bipolar systems using polyurethane insulated leads may be frequent depending on the type of polyurethane and can cause oversensing and or failure to capture. The reason for this failure is often breakage in the inner insulation. The aim of this study was to evaluate the signals created by such a short circuit. Thirty-seven patients were included in the study, 13 with failing leads with polyurethane 80A insulation, 14 with old but normally functioning leads and 10 patients with new leads. Artifacts in the form of spikes were recorded, during surgical revision, from 11 patients with failing leads (84.6%). In patients with normally functioning leads and newly implanted leads no artifacts were recorded. A significant decrease in impedance of 373.4 Ohms (99% confidence intervals 286.4-460.4, P<0.05) was noted in the failing leads compared with a decrease of only 113.0 Ohms (99%, confidence intervals 6.5-219.6, P<0.01) in the control leads. The difference between the groups was highly significant. In 10 newly implanted and five normally functioning bipolar ventricular leads similar artifacts could be created by making intermittent contact between the proximal lead connections. Thus, artifacts could be recorded from failing leads and from intact leads with artificial intermittent connection at the proximal end. Our results suggest that the failure is caused by a short circuit in the lead. This finding may have important clinical applications in the follow-up of bipolar pacing and defibrillation leads.
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Shimon Rosenheck (2000) conducted an observational in Permanent pacing leads (n=37). Failing bipolar polyurethane insulated leads vs. Normally functioning and newly implanted leads was evaluated on Artifacts in the form of spikes recorded during surgical revision. Failing bipolar polyurethane insulated pacing leads produced artifacts in 84.6% of cases (vs 0% in controls) and a significant decrease in impedance.
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