Key result
Immunization with a synthetic peptide comprising amino acids 220 to 233 of the VP4 protein primed mice for a rapid and high neutralizing antibody response upon subsequent injection with intact virus.
Authors
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May guide VP4 peptide vaccine development in animals; human translation remains untested.
Arias et al. (1989) studied Rotavirus immunization. Synthetic peptide comprising amino acids 220 to 233 of the VP4 protein was evaluated on Rotavirus neutralizing antibody response. Immunization with a synthetic peptide comprising amino acids 220 to 233 of the VP4 protein primed mice for a rapid and high neutralizing antibody response upon subsequent injection with intact virus.
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