MitraClip-data analysis of contemporary literature.

Q: What is the clinical evidence from this study?

Study design: Review. Population: Mitral regurgitation. Intervention: MitraClip vs. Mitral valve surgery or medical therapy.

Florian Deuschl; Niklas Schofer; Edith Lubos; Johannes Schirmer; Lenard Conradi; Hendrik Treede; Hermann Reichenspurner; Stefan Blankenberg; Ulrich Schäfer

doi:10.3978/j.issn.2072-1439.2015.07.38

September 1, 2015Open Access

MitraClip-data analysis of contemporary literature.

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Why the study?

Does MitraClip improve outcomes in patients with mitral regurgitation not eligible for surgery?

Structured PICO

Does MitraClip improve outcomes in patients with mitral regurgitation not eligible for surgery?

P

Population

A review of contemporary literature evaluating the safety and efficacy of the MitraClip system for treating severe mitral regurgitation in patients at high surgical risk.

I

Intervention

MitraClip (percutaneous, transseptal edge-to-edge reconstruction of the mitral valve)

O

Outcome

Safety and efficacy (reduction in mitral regurgitation, improvement in functional capacity and quality of life)

Limitations

Lack of long-term data for mitral valve surgery limits comparability with MitraClip.
Differences in patient populations between randomized trials (EVEREST II) and European registries.
Mortality benefit of MitraClip over medical treatment in high-risk surgical patients with advanced heart failure is not yet proven.

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Implication

MitraClip is a safe and effective treatment option for patients with degenerative or functional mitral regurgitation who are not eligible for surgery.

Abstract

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Discussion

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Cite This Study

Deuschl et al. (2015) conducted a review in Mitral regurgitation. MitraClip vs. Mitral valve surgery or medical therapy was evaluated.

synapsesocial.com/papers/6a967ba618aea7995cf69a19 https://doi.org/10.3978/j.issn.2072-1439.2015.07.38

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MitraClip-data analysis of contemporary literature.

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

MitraClip-data analysis of contemporary literature.

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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