Key result
A 16-year-old female developed a prolonged QT interval and torsades de pointes ventricular tachycardia on the sixth day of fluconazole treatment, which rapidly resolved after drug discontinuation.
Why the study?
Fluconazole may induce QT prolongation and in some cases subsequent life-threatening torsades de pointes.
Population
A 16-year-old female
Comparison
Fluconazole administration and cessation
Design
Case report
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May warrant QT monitoring with fluconazole in children; leaves open systematic pediatric risk assessment.
Case Report (n=1)
Fluconazole can induce life-threatening QT prolongation and Torsades de Pointes in pediatric patients, which is reversible upon drug cessation.
A 2021 study conducted a case report in Pneumonia, QT prolongation, Torsades de Pointes (n=1). Fluconazole was evaluated on Development of QT prolongation and Torsades de Pointes. A 16-year-old female developed a prolonged QT interval and torsades de pointes ventricular tachycardia on the sixth day of fluconazole treatment, which rapidly resolved after drug discontinuation.
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