Why the study?
Does the automated chemiluminescence-based VWF:CB assay improve the diagnosis and classification of von Willebrand disease in patients undergoing diagnostic testing?
Population
Patients undergoing diagnostic testing for von Willebrand disease (VWD)
Comparison
Automated chemiluminescence-based von Willebrand… vs ELISA-based VWF:CB assay
Design
Editorial
Authors
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The new automated VWF:CB assay improves the identification of types 1 and 3 VWD but requires algorithmic approaches to overcome its limitations in differentiating type 2A/2B from 2M VWD.
Does the automated chemiluminescence-based VWF:CB assay improve the diagnosis and classification of von Willebrand disease in patients undergoing diagnostic testing?
The new automated VWF:CB assay improves the identification of types 1 and 3 VWD but requires algorithmic approaches to overcome its limitations in differentiating type 2A/2B from 2M VWD.
Favaloro et al. (2017) studied this question.
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