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January 1, 2021Current Research in ToxicologyOpen Access

DNA damage by Withanone as a potential cause of liver toxicity observed for herbal products of Withania somnifera (Ashwagandha)

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Authors

SSS. Razia and A. SiddiquiNANabeel AhmedMGMausumi Goswami

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Siddiqui et al. (2021) studied this question.

synapsesocial.com/papers/6a9695a4132cd8a75e578d18https://doi.org/10.1016/j.crtox.2021.02.002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study2016 · 107 citations
  2. 2Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network2014 · 419 citations
  3. 3Toxicophores, reactive metabolites and drug safety: when is it a cause for concern?2008 · 31 citations
  4. 4Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling2010 · 159 citations
  5. 5Comprehensive review of hepatotoxicity associated with traditional Indian Ayurvedic herbs2020 · 58 citations