Key result
In heart failure patients receiving the InSync ICD, ventricular arrhythmias occurred at an overall rate of 10 episodes per 100 person-months (95% CI 8-12).
Population
142 patients with heart failure and wide QRS, mean age 65 +/- 10 years, 128 men. Etiology was ischemic in…
Design
Cohort
Follow-up
9-month median (range 0.1-24)
Authors
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Indicates persistent arrhythmic risk in HF patients on CRT-D without Class I indications; leaves open whether rates justify expanded use.
Observational (n=142)
Yes
Heart failure patients receiving cardiac resynchronization therapy with a defibrillator (CRT-D) who lack standard Class I ICD indications still experience life-threatening arrhythmic events, albeit at a lower rate than those with Class I indications.
Gasparini et al. (2003) conducted an observational in Heart failure and wide QRS (n=142). InSync ICD was evaluated on Ventricular arrhythmias (episodes/100 person-months) (95% CI 8-12). In heart failure patients receiving the InSync ICD, ventricular arrhythmias occurred at an overall rate of 10 episodes per 100 person-months (95% CI 8-12).
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