Key result
Continuous 5-fluorouracil combination chemotherapy induced acute reversible heart failure caused by severe coronary vasoconstriction in a 51-year-old male patient.
Case Report (n=1)
Continuous 5-fluorouracil chemotherapy can induce severe but reversible coronary vasoconstriction and acute heart failure, highlighting the need for prompt recognition and drug cessation.
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Alerts clinicians to reversible 5-FU cardiotoxicity; leaves open prospective studies on incidence and prevention.
Dechant et al. (2012) conducted a case report in Acute reversible heart failure caused by coronary vasoconstriction (n=1). Continuous 5-fluorouracil (5-FU) combination chemotherapy was evaluated on Acute reversible heart failure and coronary vasoconstriction. Continuous 5-fluorouracil combination chemotherapy induced acute reversible heart failure caused by severe coronary vasoconstriction in a 51-year-old male patient.
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