Population
83-year-old man with colon cancer who developed chest pain during 5-fluorouracil (5-FU) infusion
Design
Case_report
Authors
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Raises possibility of vasodilator therapy in 5-FU vasospasm; hypothesis-generating and leaves open need for prospective confirmation.
This case highlights that 5-fluorouracil cardiotoxicity can manifest as severe coronary vasospasm, which may be effectively treated with calcium channel blockers and nitrates.
Kim et al. (2012) studied this question.
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