Why the study?
Does acetylcholine infusion alter glomerular filtration rate and glomerular filtration coefficient in dogs?
Does acetylcholine infusion alter glomerular filtration rate and glomerular filtration coefficient in dogs?
In dogs, acetylcholine-induced renal vasodilation does not decrease the glomerular filtration coefficient or alter effective filtration pressure, explaining why GFR remains unchanged.
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Acetylcholine preserves GFR and Kf during vasodilation in dogs; leaves open translation to human renal hemodynamics.
Thomas et al. (1983) studied this question.
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