Key result
His bundle pacing rapidly reversed right ventricular pacing-induced cardiomyopathy, improving left ventricular ejection fraction from 35% to 60% and resolving heart failure symptoms within 7 days.
Why the study?
Does His bundle pacing improve left ventricular ejection fraction and symptoms in patients with right ventricular pacing-induced cardiomyopathy?
Case Report (n=1)
No
Does His bundle pacing improve left ventricular ejection fraction and symptoms in patients with right ventricular pacing-induced cardiomyopathy?
His bundle pacing can rapidly reverse right ventricular pacing-induced cardiomyopathy and restore left ventricular ejection fraction in patients with a narrow underlying QRS.
May support His bundle pacing in RV pacing-induced cardiomyopathy; hypothesis-generating case report requiring randomized confirmation.
KEY TEACHING POINTS•Right ventricular (RV) pacing can result in cardiomyopathy within months of chronic pacing.•His bundle pacing is a feasible alternative to biventricular pacing for treatment of suspected RV pacing–related cardiomyopathy in the setting of a narrow underlying QRS.•Physiologic His bundle pacing may result in rapid reversal of cardiomyopathy induced by RV pacing. Open table in a new tab
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Thosani et al. (2017) conducted a case report in Right ventricular pacing-induced cardiomyopathy (n=1). His bundle pacing vs. Right ventricular pacing (prior state) was evaluated on Left ventricular ejection fraction (LVEF). His bundle pacing rapidly reversed right ventricular pacing-induced cardiomyopathy, improving left ventricular ejection fraction from 35% to 60% and resolving heart failure symptoms within 7 days.
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