Population
Isolated perfused proximal convoluted tubule of the rabbit
Comparison
Reduction of bath and luminal osmolality by 90… vs Control conditions
Design
Preclinical
Authors
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Calcium rise during hypotonic swelling does not activate potassium conductance in proximal tubule cells; leaves open calcium-independent volume-regulatory pathways.
The sustained increase in basolateral potassium conductance observed when rabbit proximal tubule cells are swollen by hypotonicity or increased sodium transport is not due to a calcium-activated potassium conductance.
Beck et al. (1991) studied this question.
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