Why the study?
Does 111Indium-labelled platelet imaging accurately detect carotid artery disease compared to angiography and Doppler in patients with TIA?
Population
25 patients with transient cerebral ischaemia (TIA), 11 of whom underwent carotid endarterectomy.
Comparison
Carotid gamma imaging using autologous… vs Angiography and Doppler spectral analysis
Design
Cross-sectional, Images independently interpreted by two observers
Authors
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111In platelet imaging may aid ulcer detection in TIA; leaves open its role versus Doppler for stenosis assessment.
Does 111Indium-labelled platelet imaging accurately detect carotid artery disease compared to angiography and Doppler in patients with TIA?
111In platelet imaging is sensitive for detecting thrombogenic ulcerated plaques but less sensitive than Doppler for detecting severe carotid stenoses.
Goldman et al. (1983) studied this question.
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