Key result
Continuous infusion of Angiotensin II for 6 days increased the protein expression of NOS1 and NOS3 by approximately 200% in the myocardium of rats.
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May link Ang II to myocardial NOS upregulation in rats; leaves open translation to human hypertension or outcomes.
Tambascia et al. (2001) studied this question. Angiotensin II vs. saline was evaluated on protein expression of NOS1 and NOS3. Continuous infusion of Angiotensin II for 6 days increased the protein expression of NOS1 and NOS3 by approximately 200% in the myocardium of rats.
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