Why the study?
Do ACE inhibitors reverse structural arterial changes and improve arterial compliance in hypertensive subjects?
Population
Hypertensive subjects, particularly elderly people
Design
Review
Authors
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May support ACE inhibitor preference for vascular remodeling in hypertension; leaves open randomized outcome trials.
Do ACE inhibitors reverse structural arterial changes and improve arterial compliance in hypertensive subjects?
ACE inhibitors may be beneficial in hypertension by reversing structural arterial changes and improving arterial compliance, which disproportionately lowers systolic blood pressure.
Safar et al. (1992) studied this question.
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