Key result
Implantation of the microdiagonal blood pump in sheep maintained stable hemodynamics over 7 days without causing internal organ infarctions or enhanced free hemoglobin.
The newly developed microdiagonal blood pump provided stable hemodynamics, adequate left ventricular unloading, and no significant hemolysis or end-organ infarction in a 7-day sheep model.
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Animal data support microdiagonal pump refinement; leaves open translation to human left ventricular support.
Christiansen et al. (2004) studied Ventricular assist device testing (n=6). Microdiagonal blood pump (MDP) was evaluated on Hemodynamic and echocardiographic data, blood samples, and histologic examination. Implantation of the microdiagonal blood pump in sheep maintained stable hemodynamics over 7 days without causing internal organ infarctions or enhanced free hemoglobin.
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