Key result
Pulmonary vein isolation was feasible, safe, and completely eliminated atrial fibrillation in two patients with paroxysmal atrial fibrillation occurring late after isolated direct suture closure of an atrial septal defect.
Why the study?
Does pulmonary vein isolation eliminate paroxysmal atrial fibrillation in patients with prior direct suture closure of an atrial septal defect?
Case Report (n=2)
Does pulmonary vein isolation eliminate paroxysmal atrial fibrillation in patients with prior direct suture closure of an atrial septal defect?
Pulmonary vein isolation is a feasible, safe, and effective alternative to antiarrhythmic drugs for paroxysmal AF occurring late after direct suture closure of an ASD.
Answers are grounded in this paper and cite their sources.
PVI may be feasible after ASD suture closure; leaves open efficacy and safety in larger prospective cohorts.
Two cases of paroxysmal atrial fibrillation (AF) first occurred 15 and 36 years, respectively, after isolated direct suture closure of an atrial septal defect (ASD) and failed to be controlled by antiarrhythmic drug therapy. In these cases, an atrial transseptal procedure was feasible and no residual iatrogenic ASD was observed, even after multiple procedures. Pulmonary vein (PV) isolation was also feasible and safe and could eliminate the AF completely. PV isolation may become an alternative to antiarrhythmic drug therapy in patients with paroxysmal AF occurring late after an isolated direct suture closure of an ASD.
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Yamada et al. (2007) conducted a case report in Paroxysmal atrial fibrillation after direct suture closure of congenital atrial septal defect (n=2). Pulmonary vein isolation was evaluated on Freedom from symptomatic atrial arrhythmias without antiarrhythmic drugs. Pulmonary vein isolation was feasible, safe, and completely eliminated atrial fibrillation in two patients with paroxysmal atrial fibrillation occurring late after isolated direct suture closure of an atrial septal defect.
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