Key result
Fentanyl induction resulted in a similar incidence of relative hypoperfusion compared to thiopental-halothane induction, with defects occurring in 45% of all patients studied.
Why the study?
Does fentanyl induction compared to thiopental-halothane induction affect the incidence of relative hypoperfusion during intubation in patients undergoing elective CABG?
Population
22 patients scheduled for elective coronary artery bypass surgery
Comparison
Fentanyl (100 micrograms/kg) induction vs Thiopental (4 mg/kg) and halothane induction
Design
Cohort
Follow-up
immediately postintubation
Authors
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Relative hypoperfusion occurs frequently during CABG induction regardless of agent; leaves open whether alternative strategies can reduce incidence.
Does fentanyl induction compared to thiopental-halothane induction affect the incidence of relative hypoperfusion during intubation in patients undergoing elective CABG?
Relative hypoperfusion occurs frequently during anesthetic induction for CABG despite stable hemodynamics, regardless of whether fentanyl or thiopental-halothane is used.
Kleinman et al. (1986) studied Elective coronary artery bypass surgery (n=22). Fentanyl induction vs. Thiopental (4 mg/kg) and halothane induction was evaluated on Postintubation thallium-perfusion scan defects (relative hypoperfusion). Fentanyl induction resulted in a similar incidence of relative hypoperfusion compared to thiopental-halothane induction, with defects occurring in 45% of all patients studied.
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