Key result
Significant increases in plasma PDGF and BTG in the aortic root after PTCA, along with higher platelet counts, were associated with the development of restenosis at 6 months.
Why the study?
Are plasma levels of PDGF, beta-thromboglobulin, and platelet counts associated with the development of restenosis 6 months after PTCA?
Observational (n=26)
Are plasma levels of PDGF, beta-thromboglobulin, and platelet counts associated with the development of restenosis 6 months after PTCA?
Increases in plasma PDGF, beta-thromboglobulin, and platelet counts after PTCA are associated with angiographic restenosis at 6 months, supporting the hypothesis that platelets contribute to the restenotic process.
No takes yet. Share an insight, caveat, or question.
Post-PTCA platelet marker rises may flag restenosis risk; hypothesis-generating, no practice change without trials.
Johansen et al. (2004) conducted an observational in Percutaneous transluminal coronary angioplasty (PTCA) (n=26). Increases in plasma PDGF, BTG, and platelet counts vs. Patients without restenosis was evaluated on Restenosis evaluated by quantitative coronary angiography. Significant increases in plasma PDGF and BTG in the aortic root after PTCA, along with higher platelet counts, were associated with the development of restenosis at 6 months.
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