Key result
Patients with restenosis after coronary stenting had significantly greater platelet activation (GPIIb/IIIa ligand binding at 1 min) than those without restenosis (P=0.03).
Case-Control (n=49)
p-value: p=0.03
Increased GPIIb/IIIa ligand binding measured via wound-induced platelet activation is associated with late restenosis after coronary stenting.
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Early platelet activation may stratify restenosis risk after stenting; hypothesis-generating and requires prospective validation before clinical use.
Markovitz et al. (1996) conducted a case-control in Restenosis after coronary stenting (n=49). Restenosis vs. No restenosis was evaluated on GPIIb/IIIa ligand binding at 1 min (p=0.03). Patients with restenosis after coronary stenting had significantly greater platelet activation (GPIIb/IIIa ligand binding at 1 min) than those without restenosis (P=0.03).
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