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March 1, 1962Circulation Research17 citationsOpen Access

Pacemaker Failure in Complete Heart Block

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Why the study?

What is the cause of pacemaker failure in dogs with induced AV block and electrodes implanted in normal vs scar tissue?

Population

Dogs with induced atrioventricular conduction blocks

Comparison

Ventricular stimulation via electrodes implanted… vs Ventricular stimulation via electrodes implanted…

Design

Preclinical

Key result

Failure of ventricular stimulation in dogs with induced heart block was due to wire breakage or loss of contact, not excessive scarring, despite scar tissue requiring more power.

Authors

HAHarold M. AlbertBGBert A. GlassJAJACK A. ANDONIE

Discussion

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Overview

In a canine model of AV block, pacemaker failure was caused by mechanical issues (wire breakage or loss of contact) rather than excessive scarring.

Structured PICO

What is the cause of pacemaker failure in dogs with induced AV block and electrodes implanted in normal vs scar tissue?

P
Population
Dogs with induced atrioventricular conduction blocks undergoing ventricular stimulation via electrodes implanted into normal myocardium or scar tissue.
I
Intervention
Ventricular stimulation via electrodes implanted into scar tissue on the myocardium
C
Comparator
Ventricular stimulation via electrodes implanted into normal myocardium
O
Outcome
Cause of pacemaker failure and stimulation power requirements

In a canine model of AV block, pacemaker failure was caused by mechanical issues (wire breakage or loss of contact) rather than excessive scarring.

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Cite This Study

Albert et al. (1962) studied Atrioventricular conduction blocks. Ventricular stimulation via electrodes implanted into scar tissue vs. Electrodes implanted into normal myocardium was evaluated on Failure of stimulation. Failure of ventricular stimulation in dogs with induced heart block was due to wire breakage or loss of contact, not excessive scarring, despite scar tissue requiring more power.

synapsesocial.com/papers/6a97c1852b5b2a1696e1742bhttps://doi.org/10.1161/01.res.10.3.295
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Control of Complete Heart Block by Use of an Artificial Pacemaker and a Myocardial Electrode1958 · 124 citations
  2. 2Effect of pacemaker location on cardiac function in complete A-V heart block1963 · 36 citations
  3. 3Permanent pacemaker implantation with transvenous electrode placement in a dog with complete atrioventricular heart block, congestive heart failure and Stokes‐Adams syndrome1976 · 17 citations
  4. 4Surgical Heart Block1961 · 8 citations
  5. 5Complete Heart Block1964 · 7 citations