Key result
Human and porcine aortic valves had similar average circumferences (8.00 vs 7.90 cm), but differed in cusp dimensions, with the largest surface area in the human non-coronary cusp (1.230 cm2).
Population
12 porcine aortic valves and 12 human aortic valves
Comparison
Anatomical measurement of human aortic valves… vs Anatomical measurement of porcine aortic valves…
Design
Preclinical
Authors
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Porcine valves may need geometric adjustments for human use; leaves open functional outcomes in xenotransplantation.
Observational (n=24)
Significant anatomical differences exist between human and porcine aortic valves regarding cusp size and coaptation points, highlighting the importance of geometric considerations when using porcine valves for transplantation.
Sim et al. (2003) reported an observational. Human aortic valves vs. Porcine aortic valves was evaluated on Aortic valve circumference and cusp dimensions. Human and porcine aortic valves had similar average circumferences (8.00 vs 7.90 cm), but differed in cusp dimensions, with the largest surface area in the human non-coronary cusp (1.230 cm2).
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