Key result
Angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism was not associated with essential hypertension or vascular damage in eye fundi in a Japanese population.
Why the study?
Is angiotensin-converting enzyme (ACE) gene polymorphism associated with essential hypertension and vascular damage in a Japanese population?
Population
Essential hypertensive patients in a Japanese population with the same socioeconomic background
Design
Cross-sectional
Authors
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No association in this Japanese cross-sectional cohort; leaves open ACE polymorphism's role in hypertension across populations or designs.
Observational
Is angiotensin-converting enzyme (ACE) gene polymorphism associated with essential hypertension and vascular damage in a Japanese population?
The ACE gene insertion-deletion polymorphism does not appear to be directly responsible for essential hypertension or associated eye fundi vascular damage in this Japanese population.
Maguchi et al. (1996) conducted an observational in Essential hypertension. Angiotensin-converting enzyme (ACE) gene insertion-deletion (I/D) polymorphism was evaluated on Essential hypertension and vascular damage in eye fundi. Angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism was not associated with essential hypertension or vascular damage in eye fundi in a Japanese population.
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