Key result
In dogs implanted with a VentrAssist LVAD, left ventricular suction caused end-systolic pressure gradients of 40-160 mm Hg and total collapse of the pulmonary venous system and left heart.
Left ventricular suction during rotary blood pump support causes distal ventricular occlusion and can lead to total collapse of the pulmonary venous system and left heart, highlighting a major complication of manual speed control.
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Suction insights from canine LVAD models warrant no clinical changes; leaves open human physiological validation.
Salamonsen et al. (2015) studied Left ventricular suction complication with LVAD (n=5). VentrAssist left ventricular assist device was evaluated on Identification of the precise site and physiological changes induced by or underlying the complication of left ventricular suction. In dogs implanted with a VentrAssist LVAD, left ventricular suction caused end-systolic pressure gradients of 40-160 mm Hg and total collapse of the pulmonary venous system and left heart.
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