Key result
The abstract describes a methodology to evaluate the effects of d- and dl-propranolol on pacemaker automaticity in denervated cat hearts, but does not report any results.
Population
Isolated perfused cat heart with surgically induced heart block (cats weighing between 2 and 3 kg)
Design
Preclinical
Authors
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Describes a denervated cat heart model without results; leaves open effects of propranolol isomers on pacemaker automaticity.
This preclinical study describes a model to evaluate the role of cardiac catecholamines in the effects of propranolol isomers on pacemaker automaticity and overdrive suppression.
Kelliher et al. (1973) studied Acutely denervated heart. d- and dl-propranolol was evaluated on Atrial and ventricular pacemaker rates and overdrive suppression. The abstract describes a methodology to evaluate the effects of d- and dl-propranolol on pacemaker automaticity in denervated cat hearts, but does not report any results.
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