Key result
Digital home monitoring with centralized specialist support did not significantly improve guideline-recommended medical therapy use compared to home monitoring alone (score 0.61 vs 0.54; p=0.25).
Why the study?
It was unknown whether digital home monitoring with centralised specialist support improves medical therapy and quality of life compared with digital home monitoring alone in heart failure.
Does digital home monitoring with centralised specialist support improve the use of guideline-recommended medical therapy and quality of life in high-risk patients with chronic heart failure compared to digital home monitoring alone?
Population
202 high-risk HF patients across seven sites in the UK
Comparison
Digital home monitoring with centralised specialist support vs digital home monitoring alone
Design
Two-armed partially blinded parallel randomised controlled trial
Authors
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Adding centralized specialist support to digital home monitoring does not enhance GDMT use in high-risk HF; challenges augmentation strategies and directs research toward optimizing monitoring alone.
RCT (n=202)
partially blinded
parallel
Yes
Does digital home monitoring with centralised specialist support improve the use of guideline-recommended medical therapy and quality of life in high-risk patients with chronic heart failure compared to digital home monitoring alone?
Absolute Event Rate: 0.61% vs 0.54%
p-value: p=0.25
The addition of centralized specialist support to digital home monitoring did not significantly improve adherence to guideline-directed medical therapy or health-related quality of life in high-risk patients with chronic heart failure.
Nazarzadeh et al. (2020) conducted an RCT in chronic heart failure (n=202). Digital home monitoring with centralised specialist support vs. Digital home monitoring alone was evaluated on use of guideline-recommended medical therapy for chronic HF and major comorbidities, measured as a composite opportunity score (p=0.25). Digital home monitoring with centralized specialist support did not significantly improve guideline-recommended medical therapy use compared to home monitoring alone (score 0.61 vs 0.54; p=0.25).
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