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January 1, 1980Japanese Circulation Journal-english EditionOpen Access

Factors affecting molecular weight conversion of renin.

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Population

Isolated renin granules from dogs and rats

Design

Review

Authors

FIFumihiko IkemotoOkayama University of ScienceMKMinoru KawamuraNagano UniversityKTKazuo TakaoriOsaka Kyoiku University

Discussion

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Implication

Requires careful sample handling to avoid artifactual high-MW renin; leaves open physiologic relevance in human cardiovascular disease.

Structured PICO

P
Population
Isolated renin granules from dogs and rats
O
Outcome
Molecular weight conversion of reninsurrogate

Summarizes the biochemical mechanisms by which renin undergoes molecular weight conversion via a renin binding substance in dogs and rats.

Cite This Study

Ikemoto et al. (1980) studied this question.

synapsesocial.com/papers/6a9833f0e8073bac3ed7da5bhttps://doi.org/10.1253/jcj.44.371
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preliminary Evidence for the Conversion of Dog Renin into a Higher—Molecular—Weight Form by Cold Storage1980 · 6 citations
  2. 2Storage Form of Renin in the Dog Kidney : VII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION1978 · 9 citations
  3. 3Conversion between renin and high-molecular-weight renin in the dog1978 · 45 citations
  4. 4Characteristics of a Renin-Binding Substance for the Conversion of Renin into a Higher-Molecular-Weight Form in the Dog1979 · 28 citations