Population
Neurones freshly isolated from rat cardiac parasympathetic ganglia
Design
Preclinical
Authors
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No immediate clinical implications; leaves open whether these α1-mediated mechanisms contribute to human autonomic or arrhythmic disorders.
Noradrenaline depolarizes rat cardiac parasympathetic ganglion neurons by activating cation channels via α1-adrenoceptors and intracellular calcium signaling.
Ishibashi et al. (2003) studied this question.
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