Key result
This review highlights the physiological role of ANGPTL8 (betatrophin) in glucose homeostasis, lipid metabolism, and its association with diabetes, obesity, and metabolic syndrome.
Population
Human studies investigating metabolic diseases such as diabetes, obesity, and the metabolic syndrome
Design
Review
Authors
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ANGPTL8 merits further mechanistic study in metabolic disease; leaves open its value as biomarker or therapeutic target.
ANGPTL8 is a recently identified hormone involved in insulin resistance and lipid metabolism, making it a key target of investigation in metabolic diseases.
Abu‐Farha et al. (2017) conducted a review in Diabetes, obesity, and metabolic syndrome. ANGPTL8 (betatrophin) was evaluated. This review highlights the physiological role of ANGPTL8 (betatrophin) in glucose homeostasis, lipid metabolism, and its association with diabetes, obesity, and metabolic syndrome.
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