Highlights that patients with acute pulmonary edema often present with lactic acidosis and carbon dioxide retention, challenging the traditional teaching of isolated respiratory alkalosis.
Editorial Notes1 April 1976Emergency Management of Acute Pulmonary EdemaRONALD F. GROSSMAN, M.D., ARNOLD ABERMAN, M.D., F.R.C.P.(C)RONALD F. GROSSMAN, M.D.Search for more papers by this author, ARNOLD ABERMAN, M.D., F.R.C.P.(C)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-84-4-488_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent studies on acute pulmonary edema secondary to left ventricular failure (1, 2) have shed new light on the accompanying metabolic and ventilatory abnormalities and have reopened old questions and controversies concerning the appropriate management. Although the standard teaching in both cardiology and respiratory textbooks has been that patients with acute pulmonary edema (unless they are desperately ill) have respiratory alkalosis and no metabolic disturbances, the majority, in fact, may have lactic acidosis (3) and a large minority, perhaps as many as 30%, may have carbon dioxide retention (1, 2). The lactic acidosis is no doubt a reflection of perfusion...References1. ABERMANFULOP AM: The metabolic and respiratory acidosis of acute pulmonary edema. Ann Intern Med 76:173-184, 1972 LinkGoogle Scholar2. AVERYSAMETSACKNER WPM: The acidosis of pulmonary edema. Am J Med 48:320-324, 1970 CrossrefMedlineGoogle Scholar3. FULOPHOROWITZABERMAN MMA: Lactic acidosis in pulmonary edema due to left ventricular failure. Ann Intern Med 79 180-186, 1973 LinkGoogle Scholar4. MATTARWEILSHUBIN JMH: Cardiac arrest in the critically ill. Am J Med 56:162-168, 1974 CrossrefMedlineGoogle Scholar5. LESCHCARANOSOSMULHOLLAND MCJ: Controlled study comparing ethacrynic acid to mercaptomerin in treatment of acute pulmonary edema. N Engl J Med 279:115-122, 1968 CrossrefMedlineGoogle Scholar6. DIKSHITVYDENFORRESTER KJJ: Renal and extrarenal hemodynamic effects of furosemide in congestive heart failure after acute myocardial infarction. N Engl J Med 288:1087-1090, 1973 CrossrefMedlineGoogle Scholar7. NIXON P: Pulmonary oedema with low left ventricular diastolic pressure in acute myocardial infarction. Lancet 2:146-147, 1968 CrossrefMedlineGoogle Scholar8. GRINER P: Treatment of acute pulmonary edema: conventional or intensive care? Ann Intern Med 77:501-506, 1972 LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mount Sinai Hospital Toronto, Ontario Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Alveolar Edema 1 April 1976Volume 84, Issue 4Page: 488-488KeywordsCarbon dioxideEdemaLactic acidosisVentilators Issue Published: 1 April 1976 PDF downloadLoading ...
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Ronald F. Grossman (1976) studied this question.
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