Why the study?
Does rapid infusion of hypertonic saline cause acute hypotension mediated by transient depression of cardiac contractility in anesthetized dogs?
Population
10 anesthetized dogs
Design
Preclinical
Follow-up
5 minutes
Authors
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HTS-induced hypotension in dogs occurs via reduced SVR with increased contractility; leaves open relevance to human anesthesia.
Does rapid infusion of hypertonic saline cause acute hypotension mediated by transient depression of cardiac contractility in anesthetized dogs?
Rapid infusion of hypertonic saline causes acute, transient hypotension due to decreased vascular resistance rather than depressed cardiac contractility.
Ken et al. (1991) studied this question.
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