Key result
Overweight status, but not obesity or type 2 diabetes, was associated with significantly increased serum betatrophin concentrations, which correlated independently with insulin resistance.
Population
116 Chinese subjects, including 60 with normal glucose tolerance and 56 with type 2 diabetes mellitus.
Design
Cross-sectional
Authors
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Should not guide clinical assessment of insulin resistance; cross-sectional data leave open causal or predictive roles in metabolic disease.
Cross-Sectional (n=116)
Serum betatrophin levels are elevated in overweight individuals and correlate with insulin resistance, but are not significantly increased in obesity or type 2 diabetes.
Guo et al. (2015) conducted a cross-sectional in Obesity and Type 2 Diabetes Mellitus (n=116). Overweight status vs. Lean status was evaluated on Serum betatrophin concentrations. Overweight status, but not obesity or type 2 diabetes, was associated with significantly increased serum betatrophin concentrations, which correlated independently with insulin resistance.
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