Why the study?
Is serum ANGPTL2 concentration associated with carotid intima-media thickness in subjects with type 2 diabetes?
Population
166 subjects with type 2 diabetes without previous history of cardiovascular diseases.
Design
Cross-sectional, Ultrasound analysis was performed by a single specialized…
Key result
Serum ANGPTL2 concentration was significantly and positively correlated with carotid intima-media thickness (r = 0.220) in patients with type 2 diabetes.
Authors
Loading...
Supports ANGPTL2 as potential biomarker for subclinical atherosclerosis in T2D; hypothesis-generating and requires prospective validation.
Cross-Sectional (n=166)
No
Is serum ANGPTL2 concentration associated with carotid intima-media thickness in subjects with type 2 diabetes?
Effect estimate: r = 0.220
p-value: p=0.004
Serum ANGPTL2 concentration is independently associated with increased carotid intima-media thickness in patients with type 2 diabetes, suggesting its potential role as a biomarker for early subclinical atherosclerosis.
Jung et al. (2015) conducted a cross-sectional in Type 2 diabetes (n=166). Serum angiopoietin-like protein 2 (ANGPTL2) was evaluated on Carotid intima-media thickness (IMT) (r = 0.220, p=0.004). Serum ANGPTL2 concentration was significantly and positively correlated with carotid intima-media thickness (r = 0.220) in patients with type 2 diabetes.