Key result
Modified gender-specific ECG cut-offs improved the sensitivity of Cornell (5.5% to 16.5%) and Sokolow-Lyon (7.7% to 14.2%) criteria for diagnosing LVH in Asians, while preserving ~95% specificity.
Why the study?
Do modified gender-specific ECG criteria improve diagnostic accuracy for echocardiographic left ventricular hypertrophy in Asian populations compared to standard Western criteria?
Cross-Sectional (n=668)
Single-blind
No
Do modified gender-specific ECG criteria improve diagnostic accuracy for echocardiographic left ventricular hypertrophy in Asian populations compared to standard Western criteria?
Absolute Event Rate: 16.5% vs 5.5%
Standard Western-derived ECG criteria for left ventricular hypertrophy have poor sensitivity in Asian populations, which can be significantly improved by using lower, gender-specific voltage cut-offs.
No takes yet. Share an insight, caveat, or question.
May support modified ECG thresholds for LVH screening in Asians; hypothesis-generating and requires prospective validation before practice change.
Xu et al. (2015) conducted a cross-sectional in Left ventricular hypertrophy (n=668). Modified gender-specific ECG criteria vs. Standard ECG criteria (Cornell and Sokolow-Lyon) was evaluated on Sensitivity for diagnosing echocardiographic LVH (Cornell criteria). Modified gender-specific ECG cut-offs improved the sensitivity of Cornell (5.5% to 16.5%) and Sokolow-Lyon (7.7% to 14.2%) criteria for diagnosing LVH in Asians, while preserving ~95% specificity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: