Key result
Red cell distribution width was not associated with newly diagnosed hypertension or correlated with systolic (r=0.045, P=0.577) or diastolic blood pressure (r=0.023, P=0.772).
Why the study?
Existing data show inconsistency regarding the association between red cell distribution width and hypertension.
Is red cell distribution width associated with newly diagnosed hypertension in adults?
Case-Control (n=156)
Is red cell distribution width associated with newly diagnosed hypertension in adults?
Red cell distribution width does not appear to be a useful biomarker for newly diagnosed hypertension in this population.
Does not support RDW as a biomarker for new hypertension; leaves open its value in prospective cohorts.
The existing data have shown inconsistency about the association between red cell distribution width (RDW) and hypertension. Thus, the aim of the present study was to investigate the association between RDW and newly diagnosed hypertension among adults in Sudan. This was a case-control study conducted in Northern Sudan from July to September 2022. The cases were patients with newly diagnosed hypertension (n = 78), and the controls were healthy participants (n = 78). A questionnaire was used to collect the participants’ sociodemographic, and clinical data. RDW was measured using an automated hematology analyzer. A logistic regression analysis was performed. The univariate analysis revealed no association between sex, educational level, occupational level, RDW, and newly diagnosed hypertension. In the multivariate analysis, increasing age (adjusted odds ratio [AOR], 1.05; 95% confidence interval [CI], 1.02‒1.08) and body mass index (AOR, 1.12; 95% CI, 1.05‒1.19) were associated with newly diagnosed hypertension. No association was found between RDW and newly diagnosed hypertension. No correlation was found between RDW and systolic (r = 0.045, P = 0.577) or diastolic blood pressure (r = 0.023, P = 0.772). In conclusion, no association in RDW was found between the patients with newly diagnosed hypertension and the healthy controls.
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Hassan et al. (2023) conducted a case-control in newly diagnosed hypertension (n=156). Red cell distribution width (RDW) was evaluated on newly diagnosed hypertension. Red cell distribution width was not associated with newly diagnosed hypertension or correlated with systolic (r=0.045, P=0.577) or diastolic blood pressure (r=0.023, P=0.772).
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