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January 1, 1967Scandinavian Journal of Clinical and Laboratory Investigation

Comparison of Glass Adhesiveness and Rate of Aggregation of Blood Platelets

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Why the study?

Does the rate of platelet aggregation correlate with glass adhesiveness, and do these tests differentiate normal subjects from patients with previous myocardial infarction?

Population

Normal subjects and patients with previous myocardial infarction

Comparison

Measurement of platelet aggregation rate by… vs Measurement of platelet adhesiveness in a glass…

Design

Cross-sectional

Authors

MRM. C. RozenbergOslo University HospitalHSHelge StormorkenOslo University Hospital

Discussion

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Implication

These tests lack utility for post-MI assessment; leaves open whether refined platelet assays can stratify cardiovascular risk.

Structured PICO

Does the rate of platelet aggregation correlate with glass adhesiveness, and do these tests differentiate normal subjects from patients with previous myocardial infarction?

P
Population
Normal subjects and patients with previous myocardial infarction
I
Intervention
Measurement of platelet aggregation rate by optical density method
C
Comparator
Measurement of platelet adhesiveness in a glass bead column
O
Outcome
Correlation between platelet aggregation rate and glass adhesiveness, and difference in platelet function between normal subjects and patients with previous myocardial infarctionsurrogate

Platelet aggregation rate and glass adhesiveness do not correlate closely and neither method distinguishes between normal subjects and patients with previous myocardial infarction.

Cite This Study

Rozenberg et al. (1967) studied this question.

synapsesocial.com/papers/6a99013505ccbca0e518e8eahttps://doi.org/10.3109/00365516709093485
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Rate of Platelet Aggregation in Haemorrhagic Disease and Thrombosis1966 · 21 citations
  2. 2Platelet aggregation1962 · 353 citations
  3. 3Investigations on Adenosine Diphosphate (ADP) Induced Platelet Adhesiveness in Vitro* Part II. Studies on the Mechanism1964 · 22 citations
  4. 4ADP-Induced Platelet Adhesiveness as a Diagnostic Test in von Willebrand’s Disease)1964 · 25 citations