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December 10, 2010Journal of Clinical HypertensionOpen Access

Improvements in Insulin Sensitivity and Muscle Blood Flow in Aerobic‐Trained Overweight‐Obese Hypertensive Patients Are Not Associated With Ambulatory Blood Pressure

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Key result

Aerobic training increased VO2 max by 8% (P<.001) and improved insulin resistance (P=.039) and forearm blood flow (P<.001) in overweight-obese hypertensive patients.

Why the study?

Does aerobic training improve vascular and hormonal responses in sedentary overweight-obese hypertensive patients?

Population

Sedentary, overweight-obese hypertensive patients

Comparison

Aerobic training for 3 months vs Callisthenic exercise group for 3 months

Design

RCT, Randomized

Follow-up

3 months

Authors

PWPaulo H. WaibFaculdade de Medicina de MaríliaMGMaria Inês GonçalvesUniversidade Federal de São PauloSBSilvia Regina BarrileFaculdade Brasil

Discussion

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Implication

Supports aerobic training in overweight-obese hypertension; extends evidence for vascular and metabolic benefits independent of BP changes.

Study Design

Type

RCT

Structured PICO

Does aerobic training improve vascular and hormonal responses in sedentary overweight-obese hypertensive patients?

P
Population
Sedentary, overweight-obese hypertensive patients evaluated over a 3-month training protocol.
I
Intervention
Aerobic training for 3 months
C
Comparator
Callisthenic exercise group for 3 months
O
Outcome
24-hour blood pressure, arterial compliance, forearm blood flow, and hormonal profile at 3 monthssurrogate

Aerobic training improves vascular function and insulin resistance in overweight-obese hypertensive patients, independent of changes in ambulatory blood pressure.

Cite This Study

Waib et al. (2010) conducted an RCT in Overweight-obese hypertension. Aerobic training vs. Callisthenic exercise was evaluated on Vascular and hormonal responses (including VO2 max, insulin resistance, cortisol, forearm blood flow, and ambulatory blood pressure). Aerobic training increased VO2 max by 8% (P<.001) and improved insulin resistance (P=.039) and forearm blood flow (P<.001) in overweight-obese hypertensive patients.

synapsesocial.com/papers/6a9909552a30e7e4c5bd45fdhttps://doi.org/10.1111/j.1751-7176.2010.00393.x

Topics

Hypertension managementWomen and heart disease
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