Why the study?
Does fentanyl administration reduce adrenergic stress stimulation and alter the haemodynamic profile during isoflurane-induced hypotension in patients undergoing total hip arthroplasty?
Does fentanyl administration reduce adrenergic stress stimulation and alter the haemodynamic profile during isoflurane-induced hypotension in patients undergoing total hip arthroplasty?
The addition of fentanyl during isoflurane-induced hypotension blunts adrenergic stress responses and reduces the required concentration of isoflurane.
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Supports adding fentanyl to blunt adrenergic responses and lower isoflurane needs during hypotension; extends RCT evidence for opioid adjuncts in anesthesia.
Bernard et al. (1988) studied this question.
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