Key result
In a swine model of metabolic syndrome and chronic ischemia, resveratrol supplementation improved regional left ventricular function and preserved myocardial perfusion.
Why the study?
Does oral resveratrol supplementation improve regional left ventricular function and preserve perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome and chronic myocardial ischemia?
Population
Yorkshire swine model of metabolic syndrome and chronic myocardial ischemia
Comparison
Resveratrol 100 mg/kg/day orally supplemented to… vs High cholesterol diet alone and normal diet
Design
Preclinical
Follow-up
11 weeks total (7 weeks post-ischemia induction)
Authors
Loading...
May support further preclinical testing of resveratrol; leaves open translation to human metabolic syndrome with ischemia.
Does oral resveratrol supplementation improve regional left ventricular function and preserve perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome and chronic myocardial ischemia?
In a swine model of metabolic syndrome and chronic ischemia, oral resveratrol supplementation preserved regional left ventricular function and myocardial perfusion in nonischemic territories.
Robich et al. (2012) studied Metabolic syndrome and chronic myocardial ischemia (swine model). Resveratrol vs. High cholesterol diet (HCD) and normal diet (control) was evaluated on Regional left ventricular systolic function and myocardial perfusion. In a swine model of metabolic syndrome and chronic ischemia, resveratrol supplementation improved regional left ventricular function and preserved myocardial perfusion.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: