Population
Cultured endothelial cells derived from rabbit cardiac muscle
Design
Preclinical
Authors
Loading...
Supports divergent purinergic signaling in rabbit cardiac endothelial cells; leaves open relevance to human microvascular function.
Purine and pyrimidine nucleotides elicit multiple cellular responses in rabbit cardiac microvessel endothelial cells with similar rank orders of potency but different EC50 values, suggesting divergent coupling to cellular signaling pathways.
Mannix et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: