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June 14, 2004HeartOpen Access

Associations of components of adult height with coronary heart disease in postmenopausal women: the British women’s heart and health study

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Key result

A 1 SD (4.3 cm) increase in leg length was associated with a lower odds of prevalent coronary heart disease (OR 0.84; 95% CI 0.77-0.93) independent of potential confounders.

Why the study?

Are components of adult height associated with prevalent coronary heart disease in postmenopausal women?

Population

4,286 postmenopausal women randomly selected from 23 British towns

Design

Cross-sectional

Authors

DLDebbie A. Lawlor

Discussion

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Overview

Supports early-life factors in postmenopausal CHD risk; hypothesis-generating and should not yet change practice.

Study Design

Type

Cross-Sectional (n=4,286)

Multicenter

Yes

Structured PICO

Are components of adult height associated with prevalent coronary heart disease in postmenopausal women?

P
Population
4,286 postmenopausal women randomly selected from 23 British towns assessed for the association between components of adult height and prevalent coronary heart disease.
E
Exposure
Components of adult height (leg length, trunk length, leg to trunk ratio)
O
Outcome
Prevalent coronary heart disease (CHD)hard clinical

Main Result

Odds Ratio: 0.84 (95% CI 0.77–0.93)

Shorter leg length is independently associated with prevalent coronary heart disease in postmenopausal women, suggesting early life environmental exposures influencing skeletal growth may impact later CHD risk.

Cite This Study

Debbie A. Lawlor (2004) conducted a cross-sectional in coronary heart disease (n=4,286). Components of adult height (leg length) was evaluated on prevalent coronary heart disease (OR 0.84, 95% CI 0.77 to 0.93). A 1 SD (4.3 cm) increase in leg length was associated with a lower odds of prevalent coronary heart disease (OR 0.84; 95% CI 0.77-0.93) independent of potential confounders.

synapsesocial.com/papers/6a99640aba1957220e75dc2ehttps://doi.org/10.1136/hrt.2003.019950
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Also Consider

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  4. 4Ventilatory function, height, and mortality among lifelong non-smokers.1992 · 81 citations
  5. 5Adult height and mortality in London: early life, socioeconomic confounding, or shrinkage?1995 · 169 citations