Key result
Coronary tortuosity has minor influence on coronary blood supply at rest, but during exercise, it reduces maximal coronary blood supply by up to 14.9%.
Why the study?
Does coronary tortuosity reduce coronary blood supply at rest and during exercise in patient-specific models?
Does coronary tortuosity reduce coronary blood supply at rest and during exercise in patient-specific models?
Coronary tortuosity has a minor influence on blood supply at rest but can significantly reduce maximal coronary blood supply during exercise, providing a hemodynamic explanation for exercise-induced angina in these patients.
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May explain exertional angina in tortuosity; hypothesis-generating in animals, requires human validation.
Xie et al. (2013) studied Coronary tortuosity (n=2). Coronary tortuosity vs. Non-tortuous coronary artery models was evaluated on Maximal coronary blood supply during exercise. Coronary tortuosity has minor influence on coronary blood supply at rest, but during exercise, it reduces maximal coronary blood supply by up to 14.9%.
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