Key result
Coronary artery tortuosity, with an incidence of 12-40%, is associated with reversible myocardial perfusion defects, arterial hypertension, and technical challenges during percutaneous interventions.
Why the study?
The clinical impact of coronary artery tortuosity, including its role in inducing ischemia in non-obstructive CAD and its association with severe hypertension and PCI difficulties, required review.
Coronary artery tortuosity is increasingly recognized as a potential cause of myocardial ischemia and a significant technical challenge during percutaneous coronary interventions.
Coronary tortuosity may explain ischemia without obstruction; leaves open whether it warrants routine assessment or modified PCI approaches.
The aim of this paper was to review based on the existing literature the impact of coronary artery tortuosity on coronary pathology. Primarily, an attempt was made to establish the implication of coronary tortuosity as a physio-pathological mechanism of inducing ischemia in patients with non-obstructive coronary artery disease (CAD). Because the prevalence of tortuosity is higher in severe hypertensive patients, a second purpose of this paper was to review this association by understanding the physio-pathological processes and fluid dynamics in hypertrophic heart. Particularly, the effect of coronary tortuosity on systolic function with reference to longitudinal function and ventricular relaxation was addressed. Finally, the technical difficulties imposed by coronary tortuosity to percutaneous coronary interventions were discussed.
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Mihai et al. (2021) conducted a review in Coronary artery tortuosity. Coronary artery tortuosity, with an incidence of 12-40%, is associated with reversible myocardial perfusion defects, arterial hypertension, and technical challenges during percutaneous interventions.
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