Key result
Pharmacokinetic-guided total intravenous anaesthesia with remifentanil and propofol maintained stable intraoperative haemodynamics and allowed early extubation (150 ± 18 min) in coronary surgery.
Why the study?
Does pharmacokinetic-based total intravenous anaesthesia using remifentanil and propofol provide adequate anaesthesia and allow safe early extubation in patients undergoing surgical myocardial revascularization?
Population
32 patients undergoing on-pump coronary bypass surgery
Design
Case_series
Follow-up
postoperative period
Authors
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Hypothesis-generating for pharmacokinetic-guided TIVA in on-pump CABG; prospective trials needed before clinical adoption.
Does pharmacokinetic-based total intravenous anaesthesia using remifentanil and propofol provide adequate anaesthesia and allow safe early extubation in patients undergoing surgical myocardial revascularization?
Pharmacokinetic-based total intravenous anaesthesia with remifentanil and propofol provides stable haemodynamics and allows safe early extubation in patients undergoing on-pump coronary bypass surgery.
Guarracino et al. (2003) studied Surgical myocardial revascularization (n=32). Pharmacokinetic-guided total intravenous anaesthesia with remifentanil and propofol was evaluated on Anaesthetic efficacy, haemodynamic effects, extubation time, and postoperative analgesia. Pharmacokinetic-guided total intravenous anaesthesia with remifentanil and propofol maintained stable intraoperative haemodynamics and allowed early extubation (150 ± 18 min) in coronary surgery.
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