Key result
Human African trypanosomiasis was associated with chronic meningoencephalitis and myocarditis in all 10 cases, and chronic pancarditis in 6 cases.
Case Report (n=10)
Human African trypanosomiasis is associated with significant cardiac pathology, including chronic pancarditis, valvulitis, and conducting system lesions, in addition to myocarditis.
Suggests cardiac evaluation in HAT; hypothesis-generating and leaves open need for prospective studies.
This paper describes the pathological features of 10 cases of human African trypanosomiasis occurring in Uganda over an 8-year period. Three cases were clinically proved, and in all 10 cases chronic meningoencephalitis and myocarditis were present. There was chronic pancarditis in 6 cases, and in 3 of these there was a generalized focal valvulitis and in 2 lesions of the conducting system. Previous descriptions of carditis in human African trypanosomiasis are briefly reviewed, and the present findings are compared with some cardiomyopathies as well as American human and experimental trypanosomiasis.
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Poltera et al. (1976) conducted a case report in Human African trypanosomiasis (n=10). Human African trypanosomiasis was evaluated on Pathological features including meningoencephalitis, myocarditis, and pancarditis. Human African trypanosomiasis was associated with chronic meningoencephalitis and myocarditis in all 10 cases, and chronic pancarditis in 6 cases.
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